- 期刊
- OpenAccess
Autologous Stem Cell Transplantation for Transformed Lymphoma: Single-Center Experience
摘要
This is a single-center review of retrospectively collected computerized data and medical records of all the patients who have undergone high dose chemotherapy and ASCT for transformed lymphoma from 1999-2014. The primary endpoint of the study was overall survival (OS) and secondary endpoint was progression free survival (PFS). A total of 27 patients with histological transformation were identified. This included transformation from follicular lymphoma Grade 1-3A and non-follicular indolent lymphoma, synchronous and asynchronous presentation. All transformed to diffuse large B cell lymphoma. 33% were chemotherapy naive prior to transformation. Median follow up was 47 months. For the entire cohort OS at 3 years was 73% and PFS = 82%. The treatment has low risk for nonrelapse mortality providing durable remission.
延伸閱讀
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