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Hepatitis C Virus Infection and Kidney Disease

並列摘要


Chronic hepatitis due to hepatitis C virus (HCV) infection is highly prevalent throughout the world. In addition to causing chronic hepatitis, HCV is associated with extrahepatic manifestations, especially renal. The exact mechanism through which HCV infection modulates the development and progression of kidney disease is unknown. Although several studies have examined an association of HCV infection with Glomerular Filtration Rate (GFR), their results have been inconsistent. On the other hand, studies have consistently found an association between HCV and albuminuria. Patients with unknown cause of proteinuria should be screened for HCV infection and upon positive results be closely followed up for signs and symptoms of deteriorating kidney condition.

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