Lung cancer is the leading cause of cancer death in Taiwan for a long time. Therefore, lung cancer screening is important to find the lesion early. In the past, chest X-ray was considered as screening tool for early detection of lung cancer. Recently, noise reduction techniques enable CT to scan at a very low radiation dose, such as low-dose chest CT. This leads to increase the amount of LDCT for lung cancer screening in clinical practice. In this study, we aimed to compare the nodule evaluation in LDCT before and after training for medical radiation technologists in different working experiences. Our results demonstrated that both trained senior and junior technologists have improvement in nodule evaluation of LDCT and this improvement was more significantly found in junior technologist. We suggested that this training courses should be integrated into medical radiation technologist's Post Graduate Year program to improve the nodule evaluation in LDCT.