This paper discusses the significance of Shakespeare's plays which contain bubonic plague in light of our disastrous situation of the COVID-19 pandemic. The situation of bubonic plague is found to be reflected in the Bard's plays, for example, Romeo and Juliet, The Life of Timon of Athens, The Tragedy of Coriolanus, Macbeth, Twelfth Night, Much Ado about Nothing, and King Lear. Besides, the widely discussed lawsuit occurred in late 1603 might have influenced Shakespeare's writing about King Lear. This paper, utilizing New Criticism close reading, provides an informative overview of Shakespeare's life in the shadow of plague and his references to the disease in his plays. This article argues that plagues and pandemics can work as metaphors to symbolize diseases, moral decadence, and lovesickness.