摘要
肺硬化性肺泡細胞瘤（pulmonary sclerosing pneumocytoma, PSP）為一少見的肺部良性腫瘤，好發於中年女性。影像上常可見單顆、邊界清晰、靠近肋膜的病灶。病患一般無臨床症狀，在胸部影像上意外發現異常，少數有的症狀包含咳嗽、胸痛、咳血等。典型的病理特徵則有實質、乳突、硬化與出血四種型態。個案為一年輕女性，因例行健康檢查之胸部X光片發現一結節，經電腦斷層導引肺部切片後診斷為肺硬化性肺泡細胞瘤。本文簡要介紹此疾病的臨床特徵與診斷治療。
參考文獻
Devouassoux–Shisheboran M, Hayashi T, Linnoila R, et al. A clinicopathologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies. Am J Surg Pathol 2000;24:906-16.
Baysak A, Oz A, Moğulkoç N, et al. A rare tumor of the lung: Pulmonary sclerosing hemangioma (pneumocytoma). Respir Med 2013;107:448-50.
Corrin B, Nicholson A. Pathology of the lungs. 3rd ed. Elsevier 2011.
Aihara T, Nakajima T. Sclerosing hemangioma of the lung: Pathological study and enzyme immunoassay for estrogen and progesterone receptors. Acta Pathol Jpn 1993;43:507-15.
Wu C, Chang Y, Lee Y. Expression of the estrogen receptor β in 37 surgically treated pulmonary sclerosing hemangiomas in comparison with non–small cell lung carcinomas. Hum Pathol 2005;36:1108-12.
延伸閱讀
- 莊凡毅、陳威志（2016）。胸腔病例（三三一）肺部動靜脈畸形。臨床醫學月刊，78(5)，294-298。https://doi.org/10.6666/ClinMed.2016.78.5.024
- Tsai, T. Y., Hwang, J. J., Wang, T. H., Cheng, Y. J., Yang, S. F., & Huang, M. S. (2004). 肺臟硬化性血管瘤：－病例報告. 胸腔醫學, 19(5), 406-411. https://doi.org/10.29806/TM.200410.0015
- 杞建業、張書綸、彭殿王（2018）。胸腔病例（三四五）肺部蘭格罕氏組織細胞增生症。臨床醫學月刊，81(2)，110-116。https://doi.org/10.6666/ClinMed.201802_81(2).0021
- Shu, G. H., Hur, T., & Chang, J. M. (1995). 肺部硬化性血管瘤－一病例報告. 中華放射線醫學雜誌, 20(3), 251-255. https://www.airitilibrary.com/Article/Detail?DocID=10188940-199509-20-3-251-255-a
- 吳佳儒、江起陸（2020）。胸腔病例（三六六）肺動靜脈畸形。臨床醫學月刊，85(5)，316-321。https://doi.org/10.6666/ClinMed.202005_85(5).0056