透過您的圖書館登入
IP:18.216.83.240

摘要


搔癢是尿毒症患者相當常見的主訴,對於患者的生活品質帶來相當大的困擾。尿毒搔癢症的機轉相當複雜,而近幾年的研究使得我們對於其病生理機轉有更多的認識,許多新藥物也據此研發。本文簡介尿毒搔癢症的臨床表現、病生理機轉、以及治療選擇。

參考文獻


Satti MZ, Arshad D, Javed H, et al. Uremic Pruritus: Prevalence and Impact on Quality of Life and Depressive Symptoms in Hemodialysis Patients. Cureus 2019;11:e5178.
Hu X, Sang Y, Yang M, et al. Prevalence of chronic kidney disease-associated pruritus among adult dialysis patients: A meta-analysis of cross-sectional studies. Medicine 2018;97: e10633.
Mettang T, Kremer AE. Uremic pruritus. Kidney international 2015;87:685-91.
Umeuchi H, Togashi Y, Honda T, et al. Involvement of central μ-opioid system in the scratching behavior in mice, and the suppression of it by the activation of κ-opioid system. Eur J Pharmacol 2003;477:29-35.
Ikoma A, Steinhoff M, Ständer S, et al. The neurobiology of itch. Nat Rev Neurosci 2006;7:535-47.

延伸閱讀