Thiopental extravasation which would cause tissue edema and necrosis in rapid progression by chemical reaction and vascular spasm is a potentially serious complication in anesthesia. Early diagnosis and treatment may bear a favorable outcome. A patient who sustained thiopental extravasation and received local injection of lidocaine and local application of EMLA (Eutectic Mixture of Local Anesthetics) for treatment with excellent results is presented hereunder.
2.5% Thiopental意外地注射至靜脈血管之外時,可以造成疼痛,紅腫,組織壞死,甚至壞疽。一旦發生,後果難料。嚴重時病患更需接受植皮治療。本文乃報告一thiopental外滲至組織之病例,其麻醉過程及外滲之處理,特別是EMLA(Eutectic Mixture of Local Anesthetics)藥膏之應用,並參考相關文獻,針對其病理生理,治療方針,藥理作用,做一探討。