Oxytocin is widely used in obstetric settings to stimulate uterine contraction and prevent postpartum hemorrhage. Its adverse effects which include transient hypotension and increase heart rate could be life-threatening in patients with fixed cardiac output or hypotension resulting from hemorrhage. We reported two cases suspected to have preexisting prolonged Q-T interval syndrome (PQTS) who developed ventricular tachycardia immediately after intravenous injection of oxytocin. Anesthetic management of and use of oxytocic agents in patients with PQTS were discussed.
催產素(Oxytocin)是一種子宮收縮劑,常被廣泛使用於產科病人以刺激子宮肌肉收縮來避免產後大量出血。它的副作用包括短暫性的低血壓和心跳加速,對固定心輸出量或出血性低血壓的病人而言應甚至可以致命。在此,我們報告兩位具Q-T間距延長症候群的病人在靜脈注射催產素後引發心室博動過速的案例並討論其麻醉處置。