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非ST上升型急性冠心症住院患者的發病年齡與身體質量指數相關性之探討

The Correlation Between Body Mass Index and the Age of Inpatients With Non-ST-Segment-Elevation Myocardial Infarction (NSTEMI)

摘要


身體質量指數(body mass index, BMI)已是世界公認可用來分類肥胖與體脂肪的重要工具。肥胖是影響冠狀動脈疾病的主要危險因素之一,並且肥胖患者大多數都連帶患有各種慢性疾病,如高血壓、糖尿病、高血脂。本研究目的在探討非ST上升型急性冠心症(non-ST-segment-elevation myocardial infarction, NSTEMI)患者首次及本次發病年齡與BMI之相關性。本研究為病歷回溯型研究,收集自2019年10月1日至2020年6月30日入住南部某醫學中心心臟內科加護病房,診斷為NSTEMI患者且須執行心導管手術病人之病歷相關資料,共收案124位個案,排除10位資料不完整者及1位死亡個案,最後納入113位個案進行分析。按照國內國民健康署BMI標準,將研究對象分為體重不足/正常體位(BMI ≤ 23.9 kg/m^2)、體重過重(BMI: 24~26.9 kg/m^2)、肥胖(BMI ≥ 27 kg/m^2)共三組。研究結果發現,體位較重的肥胖組是三組中本次發病年齡最年輕的族群,平均年齡為60.6±2.0歲,發現診斷為NSTEMI之肥胖族群中以64歲以下患者比例較高,且明顯有代謝性疾病病史,如高血脂與糖尿病等問題出現。而體重不足/正常體位組是三組中首次發病年齡最年長,平均年齡為67.8±1.7歲。以偏相關性檢定NSTEMI首次及本次發病年齡與BMI之獨立相關性,結果達顯著性差異,p<0.001。故首次與本次發生NSTEMI可能常見於高體位的年輕肥胖成年人。

並列摘要


Body mass index (BMI) is widely recognized as a tool to classify obesity and adiposity. Obesity is well recognized as a risk factor influencing coronary artery disease, and obese patients tend to have several chronicle diseases such as hypertension, type II diabetes mellitus, and hyperlipidemia. This research aimed to explore the correlation between age and BMI for inpatients diagnosed with non-ST-segment-elevation myocardial infarction (NSTEMI). The retrospective medical chart review of patients admitted to the cardiology intensive care unit of a medical center in Tainan city with a diagnosis of NSTEMI and received cardiac catheterization treatment during October 2019, and June 2020 were identified, of which medical records of 124 patients were collected, excluding 10 incomplete data and one expired patient; a total of 113 patients were analyzed. The BMI was divided into underweight/normal weight, overweight, and obesity based on international standards. The correlations of BMI and age among these groups were examined. Obesity was the youngest among the groups, with the age of this NSTEMI occurring an average of 60.6 ± 2.0 years old and with comorbidities of type II diabetes and hyperlipidemia. These results indicated that the < 64 years old obese patients tended to be a higher percentage and suffered from metabolic syndromes such as hyperlipidemia and diabetes mellitus. The underweight/ normal weight group was the eldest, with the age of the first NSTEMI occurring at an average of 67.8 ± 1.7 years old. Based on the partial correlation analysis, the correlation between BMI and the age of the first and current diagnosis of NSTEMI is of significant difference (p < 0.001). This study shows that the age of the first NSTEMI and current diagnosis of NSTEMI may tend to occur in younger adults with high BMI; early preventive strategies may be needed.

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