臺灣北部三地區家蠅對二氯松及亞特松之抗性機制

Resistance Mechanisms of Houseflies to Dichlorvos and Pirimiphos-methyl in Three Areas of Northern Taiwan

廖信昌(Sin-Chung Liao) ； 徐爾烈(Err-Lieh Hsu) ； 馬甚津(William Can-Jen Maa)

《中華昆蟲》 16卷1期 (1996/03) Pp. ii+13-23

https://doi.org/10.6660/TESFE.1996002

摘要

與感性品系相較，羅東、深坑及基隆地區家蠅對二氯松之抗藥性分別為31,18及21倍；對亞特松之抗性分別為14, 38及94倍。根據生物檢定及活體外酵素活性之結果，顯示羅東家蠅對二氯松及亞特松之抗性機制包括所有可能之解毒代謝性酵素，深坑家蠅對此二藥之抗性機制主要為酯酶及神經部位不敏感(如AChE不敏感性)，而基隆家蠅對二氯松之主要抗性機制為雙功能加氧酶，對亞特松之抗性機制同樣如羅東家蠅包括所有可能之解毒代謝酵素，然而降低昆蟲表皮對藥劑之穿透速率及AChE之不敏感性為北台灣三地區家蠅共同普遍具備之抗性因子。

關鍵字

家蠅 ； 抗藥性 ； 協力劑

並列摘要

Luotung (LT), Suinkeng (SK) and Keelung (KL) housefly populations were examined for insecticide resistance. When compared with a susceptible (S) strain, resistance to dichlorvos by wild (R) houseflies ranged from 18 to 31 fold; resistance to pirimiphos-methyl of R flies ranged from 14 to 94 fold. Bioassay synergist and in vitro enzyme activity studies showed that the mechanisms of resistance to dichlorvos and pirimiphos-methyl for LT flies, included increased activities of microsomal oxidase, glutathione transferase and general esterase. The general esterase and acetylcholinesterase (AChE) insensitivity may be involved in the resistance mechanism of SK flies to these 2 insecticides. However, microsomal oxidase was the major contributor to the resistance to dichlorvos, as well as all possible metabolized detoxification enzymes involved in the resistance to pirimiphos-methyl for KL houseflies. Finally we suggest that the reduced penetration of insecticides through the cuticle, and insensitivity to AChE were the common important resistant factors in the houseflies of these 3 areas in northern Taiwan.

並列關鍵字

Housefly ； insecticide resistance ； synergist