Androgen-Producing Adrenocortical Carcinoma: A Case Report

Ju-Mei Liu ； Hua-Fen Chen ； Pei-Hwei Chen

《Formosan Journal of Endocrinology and Metabolism》 2卷4期 (2011/10) Pp. 97-101

https://doi.org/10.6856/FJEM.201110_2(4).0002

摘要

Adrenocortical carcinoma is an extremely rare malignant tumor. Symptoms may result from hormonal (cortisol, androgen, estrogen or aldosterone) oversecretion, the mass effect or/and metastases. Complete tumor removal offers the best chance for long-term survival; otherwise, the estimated 5- year survival rate is less than 30%. We reported a case of left androgen-producing adrenocortical carcinoma with the initial presentations of hirsutism and hair loss, who received left adrenalectomy. In a series of follow-up studies for 10 months after tumor resection, serum dehydroepiandrosterone-sulfate (DHEA-S) and testosterone remained in normal range without evidence of local recurrence or metastases on image survey.

關鍵字

Androgen-producing adrenaocortical carcinoma ； hirsutism ； hyperandrogenism dehydroepiandrosterone- sulfate (DHEA-S)