青梅果提取物應用於健康管理之研究

許多研究指出青梅果提取物（prunus mume fruit extract）具有抗氧化、抗發炎、抗癌等特性，同時因其具有高生物利用率，因此，除了在醫療上面的應用外，亦可用作為膳食補充劑。然而，至今並未有較完整研究針對青梅果提取物對於人體血脂中之三酸甘油酯（Triglyceride, TG, Triacylglycerol, TAG, or Triacylglyceride，血脂肪）及膽固醇（Cholesterol）之調節作用進行綜合的研究分析。本研究旨在了解青梅果提取物對於人體血脂是否具有調節之作用。本研究於2012年8月至同年9月進行為期一個月之實驗，資料整理自台中市某一檢驗所檢驗數據分析，參與實驗人員共48人，隨機區分兩組進行單盲人體試驗，年齡分布於28至67歲之間，實驗組平均年齡51.38歲，安慰劑組平均年齡50.35歲。男女性比例為50%比50%，實驗組男女性比例為62.5%比37.5%，安慰劑組男女性比例為37.5%比62.5%。青梅果來自南投縣，經提取青梅果後，以每人三餐飯後每次食用2公克提取物（青梅果提取物50%、麥芽糊精50%）劑量（6g/d），區分實驗組（n=24），以及安慰劑組之對照組（n=24），進行一個月食用前後之膽固醇、三酸甘油酯、高密度膽固醇、以及低密度膽固醇之比較分析。本研究以SPSS進行分析，結果顯示服用青梅果提取物對於上述各項指標呈現顯著緩解作用；同時發現對於不同性別之服用者有不同之顯著性。

關鍵字

健康管理；青梅果提取物；膽固醇；三酸甘油酯

並列摘要

Many studies have pointed out that the prunus mume fruit extract has anti-oxidation, anti-inflammatory, anti-cancer and other characteristics, and because of its high bioavailability, it can be used as a dietary supplement in addition to medical applications. However, no comprehensive research has been conducted on the regulation of the prunus mume fruit extract on triglyceride and cholesterol in human blood lipids. The purpose of this study was to understand whether the prunus mume fruit extract has a regulating effect on human blood lipids. This study conducted a one-month experiment from August 2012 to September of the same year. The data were collected from the results of an institute of medical laboratory in Taichung City. A total of 48 participants participated in the experiment. Two groups were randomly divided into single-blind trials. The age was distributed between 28 and 67 years, the mean age of the experimental group was 51.38 years old, and the mean age of the placebo group was 50.35 years old. The proportion of male to female was 50% to 50%. The male-female ratio in the experimental group was 62.5% to 37.5%, in the placebo group was 37.5% to 62.5%. The prunus mume fruits were from Nantou County, Taiwan, which were extracted by water. Each person (experimental group, n = 24) took 2 grams of extract dose (6 g/d) after meals (prunus mume fruit extract 50%, maltodextrin 50%), the placebo group were given by other substitutes, and a comparative analysis of cholesterol, triglycerides, high-density cholesterol, and low-density cholesterol was then examined before and after one month of consumption. The results revealed that the group taking prunus mume fruit extract showed significant relief for all the above indicators; it was also found that there existed significant differences in between different genders.

並列關鍵字

health management ； prunus mume fruit extract ； cholesterol ； triglyceride

參考文獻

Yanaki M, Kobayashi M, Aruga A, Nomura M, Ozaki M. In Vivo Antitumor Effects of MK615 Led by PD-L1 Downregulation. Integr Cancer Ther. 2018 Apr 1:1534735418766403.

Prunus mume (Sieb.) Sieb & Zucc., 1836 。梅《臺灣生物多樣性資訊網-TaiBIF》。http://taibif.tw/zh/namecode/204176?page=1，2018/07/11