Synchronous colorectal cancer (CRC) is characterized by multiple cancer lesions found in a single patient upon diagnosis. We report about a 68-year-old male patient with quadruple colon cancer who initially presented with intermittent abdominal pain and with positive fecal occult blood test. Preoperative colonoscopy and computed tomography scan have suggested synchronous colon cancer lesions. He underwent subtotal colectomy with ileorectal anastomosis and recovered well. No major complications were noted. Pathological examination confirmed the diagnosis of quadruple colon cancer. Synchronous CRC is a rare type of cancer. Thus, in this study, its distinctive clinicopathological features as well as diagnosis, management, and prognosis were assessed.