The purpose of the study was to investigate the effects of self-instruction strategies on MRT- taking skills for three elementary students with intellectual disabilities. A multiple probe design across three subjects was adopted. The researcher collected quantitative and qualitative data during the study. The study contained baseline, intervention /generalization, and follow-up phases. The study results were: (a) three elementary school students with intellectual disabilities acquired MRT-taking skills using self-instruction strategies; (b) three elementary school students with intellectual disabilities maintained MRT-taking skills using self-instruction strategies; and (c) three elementary school students with intellectual disabilities had partial stimulus generalization on MRT-taking skills using self-instruction strategies. The result indicated the following implications: self-instruction strategies could promote MRT-taking skills for elementary school students with intellectual disabilities by using task analysis, and verbalized self-instruction.