The Effectiveness of Butorphanol Infusion in Patients Undergoing Awake Fibreoptic Nasal Intubtion

Tingju Hu ； Wenqian Li ； Junqing Li ； Chao Chen ； Xiaohua Zou

《World Scientific Research Journal》 6卷10期 (2020/10) Pp. 39-43

https://doi.org/10.6911/WSRJ.202010_6(10).0007

摘要

Objective To evaluate the efficacy of butorphanol infusion in difficult airway patients undergoing awake fibreoptic nasal intubation. Method Sixty patients with difficult airway in our hospital, ASA I or II, aged 18-70 years and weighing 48-80kg, were selected and dandomly divided into two groups (n=30 each): butophanol group (group B) and saline group (group N). The patients of the two group entered the room and injected penehyclidine after established venous access. The two group all injected dexmedetomidine and remifentanil continually for 10min. Then gave several drops of ephedrine to the nasal cave to sistolic vescular and 2% lidocaine for pharynx andlarynx topical anesthesia. Group B was intravenously injected with butorphanol 1mg 5min before intubation and group N was intravenously injected with 0.9% normal saline 5min before intubation. Hemodynamic changes were recorded. ramsay score, reflection of tussis, patients' satisfaction and anesthesiologist's satisfaction were recoreded. Result Compared with Group N the HR and MAP of Group B at T1 was statistically lower. The ΔHR and ΔMAP of the two group was statistically significant lower, too. (P＜0.05). There is no statistically significant difference between the two groups in SpO_2 at T0 and T1 (P＞0.05). Ramsay score, intubation time, patients' satisfaction, anesthesiologist's satisfaction were statistically significant compared with group N(P＜0.05). Conclusion Butorphanol can be effectively used in difficult airway patients through nasal intubation by bronchofiberscope, reduce the cardiovascular reflection and intubation time, improve patient's comfort and anesthesiologists' satisfaction. Clinical Trials Registration: The trial was registered prospectively at ChiCTR (ChiCTR2000 033607).

關鍵字

Butorphanol ； Topical anesthesia ； difficult airway ； Bronchofiberscope ； Awake endotracheal intubation

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