In order to study the economic radiation ability of central cities to surrounding cities, this paper uses panel data of 20 cities in Guangdong Province from 2003 to 2016 to empirically analyze the impact of economic growth of Guangzhou as a central city on surrounding cities. The empirical results show that Guangzhou's economic growth has a radiation effect on the economic development of surrounding cities, and this effect is a positive radiation effect. The further research of this paper found that from the perspective of various industries, the secondary industry and tertiary industry in central cities have a radiating effect on surrounding cities, and they both promote the economic growth of surrounding cities to a certain extent; The secondary industry has a greater impact on the economic growth of surrounding cities. Finally, this article puts forward policy recommendations for further exerting the radial function of the central city.