The sense of responsibility of Chinese youth in the new era has been fully demonstrated during the period of epidemic prevention and control. The sense of responsibility of young people in the new era mainly comes from Xi Jinping's view of youth responsibility, and "having ideals, abilities and responsibilities" constitutes the core meaning of Xi Jinping's view of youth responsibility on ideals and beliefs. From the influence of the May 4th spirit, the core of the May 4th spirit guides and encourages young people to actively devote themselves to the great practice of socialism with Chinese characteristics. From socialist values, value orientation constitutes the spiritual pillar of Xi Jinping's view of youth responsibility. In order to further strengthen the sense of responsibility of young people in the new era, we should not only strengthen the teaching of social responsibility consciousness Education, but also young people with their own down-to-earth efforts, always remember responsibility and responsibility and constantly struggle.