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Efficacy Analysis of Recombinant Human Pro‐Urokinase Combined with Percutaneous Coronary Intervention in the Treatment of Acute ST‐Segment Elevation Myocardial Infarction

摘要


Purpose This article discusses the clinical therapeutic effect of recombinant human pro-urokinase combined with percutaneous coronary intervention in the treatment of acute ST‐segment elevation myocardial infarction. Method A retrospective analysis of 89 patients with acute ST‐segment elevation myocardial infarction admitted in our hospital from January to December 2020 was conducted and divided into the treatment group (n=46) and the control group (n=43) according to different treatment options. The control group was treated with percutaneous coronary intervention, and the treatment group was treated with recombinant human pro‐urokinase based on that. The levels of LVEF, LVEDD, CK‐MB, hs‐CRP, and coronary artery recanalization rates were compared between the two groups. Results Before the operation, there was no statistically significant difference in the levels of LVEF and LVEDD between the two groups (P>0.05). After the operation, the LVEF levels of the two groups increased, and the LVEDD levels decreased. The difference between the groups was not statistically significant (P>0.05). Similarly, before the operation, there was no significant difference in the levels of CK‐MB and hs‐CRP between the two groups (P>0.05). After the operation, the levels of CK‐MB and hs‐CRP in the two groups decreased, but the levels of the treatment group were lower than those of the control group. The difference between the groups was statistically significant (P<0.05). Conclusion Recombinant human pro‐urokinase combined with percutaneous coronary intervention can achieve better results in the treatment of acute ST‐segment elevation myocardial infarction, which can further reduce the levels of CK‐MB and hs‐CRP and increase the coronary recanalization rate.

參考文獻


Jinghong Zhao, Yan Qiao, Tao Liu, et al. Study on the application effect of low-dose recombinant human pro-urokinase in patients with acute ST-segment elevation myocardial infarction in the emergency percutaneous coronary intervention [J]. Journal of Practical Cardiocerebral Pulmonary Vascular Disease, 2021, 29(09): 77-81+93.
Xiaofeng Liu and Yingfu Yao. The clinical effect of recombinant human pro-urokinase combined with percutaneous coronary intervention in the treatment of acute ST-segment elevation myocardial infarction [J]. Henan Medical Research, 2021, 30(19): 3563-3565.
Chinese Medical Association Cardiovascular Diseases Branch, Chinese Journal of Cardiovascular Diseases Editorial Committee. Guidelines for the diagnosis and treatment of acute ST-segment elevation myocardial infarction [J]. Chinese Journal of Cardiovascular Diseases, 2010, 38 (07): 675-687.
Junfeng Wang and Xiaofeng You. Application of recombinant human pro-urokinase combined with PCI in patients with acute ST-segment elevation myocardial infarction [J]. Modern Diagnosis and Treatment, 2021, 32(11): 1751-1752.
Xiaohui Zhao, Shuangdong Lu, Jie Chen, et al. Study on the preventive effect of recombinant human pro-urokinase on the no-reflow phenomenon after percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction [J]. Journal of Practical Cardiocerebral Pulmonary Vascular Disease, 2021, 29(06): 105-109.

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