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Stroke is one of the most important causes of epilepsy. With the advancement of medicine, the mortality rate of stroke keeps decline, then the stroke survivors have become a high-risk group of epilepsy due to damage to the brain cells. The first edition of the "Guideline for Post-Stroke Epilepsy Management" co-edited by Taiwan Epilepsy Society and Taiwan Stroke Society in 2015. During the past six years, many anti-epileptic drugs with new mechanisms have been launched. After the consensus of Taiwan Epilepsy Society and Taiwan Stroke Society, we had updated the post-stroke epilepsy guideline, which divided into six sections including the definition and epidemiology of post-stroke epilepsy, the pathophysiology diagnosis, risk factors and prognostic models, management and treatment, and drug-drug interactions. The recommendation level is based on the American Heart Association/American Stroke Association (AHA/ ASA) treatment guidelines: the class of recommendation (COR) is divided into I, IIa, IIb, III, and the level of evidence [LOE]) is divided into A, B-R, B-NR, C-LD, C-EO. The level of evidence provides treatment recommendations, hoping to help all the medical staff in managing post-stroke epilepsy.

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