透過您的圖書館登入
IP:3.15.221.165
  • 期刊
  • OpenAccess

Impact of green tea extract on serum lipid of postmenopausal women: A randomized controlled trial

摘要


Background: This study aimed to evaluate the impact of green tea extract on serum lipid level in postmenopausal women. Method: In this randomized controlled trial 100 postmenopausal women with an abnormality in at least one lipid profile were recruited and randomly assigned to one of the two groups: green tea extract (n = 50) and control group (n = 50). The intervention group received two capsules (400 mg) of green tea extract two times daily; the control group received a placebo for 4 weeks. The serum level of the lipid profile (total cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL), triglyceride, and fasting blood sugar) was measured at baseline and 4 weeks after intervention. Results: In total, 79 women completed the study. The mean total cholesterol in the green tea group was significantly decreased after 4 weeks of intervention (mean difference -18.1 vs. -5 mg/dL in the green tea and placebo groups, p < 0.04). The triglyceride and LDL also decreased significantly in the green tea group compared to the control group (p = 0.002 and p = 0.04 respectively). The level of HDL and fasting blood sugar did not change within the group and between groups. Conclusion: Green tea extract is cost-effective way to decrease lipid profile in postmenopausal women without major side effects. Using this herb is recommended in women who have slight lipid profile abnormalities.

參考文獻


Derby CA, Crawford SL, Pasternak RC, et al. Lipid changes during the meno-pause Transition in relation to age and Weight the study of Women's health across the Nation. Am J Epidemiol. 2009;169(11):1352-1361. https://doi.org/10.1093/aje/kwp043
Ahmad RS, Sadiq Butt M, Tauseef Sultan M, et al. Preventive role of green tea catechins from obesity and related disorders especially hypercholesterolemia and hyperglycemia. J Transl Med. 2015;13:79. https://doi.org/10.1186/s12967-015-0436-x
Koo SL, Noh SK. Green tea as inhibitor of the intestinal absorption of lipids: potential mechanism for its lipid-lowering effect. J Nutr Biochem. 2007 Mar;18(3):179-183. https://doi.org/10.1016/j.jnutbio.2006.12.005
Suliburska J, Bogdanski P, Szulinska M, et al. Effects of green tea supplementation on elements, total antioxidants, lipids, and glucose values in the serum of obese patients. Biol Trace Elem Res. 2012 Dec;149(3):315-322. https://doi.org/10.1007/s12011-012-9448-z
Onakpoya I, Spencer E, Heneghan C, et al. The effect of green tea on blood pressure and lipid profile: a systematic review and meta-analysis of randomized clinical trials. Nutr Metab Cardiovasc Dis. 2014 Aug;24(8):823-836. https://doi.org/10.1016/j.numecd.2014.01.016

被引用紀錄


Kang, B. B., & Chiang, B. H. (2022). A novel phenolic formulation for treating hepatic and peripheral insulin resistance by regulating GLUT4-mediated glucose uptake. Journal of Traditional and Complementary Medicine, 12(2), 195-205. https://doi.org/10.1016/j.jtcme.2021.08.004
Nagamma, T., Konuri, A., Bhat, K. M., Udupa, P., Rao, G., & Nayak, Y. (2022). Prophylactic effect of Trigonella foenum-graecum L. seed extract on inflammatory markers and histopathological changes in high-fat-fed ovariectomized rats. Journal of Traditional and Complementary Medicine, 12(2), 131-140. https://doi.org/10.1016/j.jtcme.2021.07.003

延伸閱讀