A review of antioxidant and pharmacological properties of phenolic compounds in Acacia confusa

Huan-You Lin ； Tzu-Cheng Chang ； Shang-Tzen Chang

《Journal of Traditional and Complementary Medicine》 8卷4期 (2018/10) Pp. 443-450

https://doi.org/10.1016/j.jtcme.2018.05.002

摘要

In the present review article, the phytochemical, antioxidant and pharmacological studies are congregated and summarized concerning the current knowledge of the phenolic compounds of a traditional medical plant Acacia confusa in Taiwan. This plant is native to Taiwan and South-East Asia. It possesses major pharmacological activities, including antioxidant and radical scavenging activity, hepatoprotective effect, xanthine oxidase inhibition, semicarbazide-sensitive amine oxidase inhibition, angiotensin I converting enzyme inhibition, antihyperuricemic effect and anti-inflammatory activity. Phenolic compounds, especially flavonoids, flavonol glycoside and phenolic acid derivatives, are the main phytochemical compounds isolated from different plant parts of A. confusa. Recent interest in this species has focused on pharmacological investigations of the phytochemicals which exhibit potent antioxidant activity based on the multiple phenolic functionalities. The consequence of this review will further extend the potential applications of this plant and offer persuasive support to its future use in the fields of clinical medicine and health functional food.

關鍵字

Antioxidant ； Flavonoids ； Pharmacological properties ； Acacia confuse ； Leguminosae ； Functional food

參考文獻

Sen P, Kemppainen E, Orešič M. Perspectives on systems modeling of human peripheral blood mononuclear cells. Front. Mol. Biosci. 2018. https://doi.org/10.3389/fmolb.2017.00096

Ho ST, Tung YT, Chen YL, Zhao YY, Chung MJ, Wu JH. Antioxidant activities and phytochemical study of leaf extracts from 18 indigenous tree species in Taiwan. Evid-based Complement Altern Med.. 2012, 215959 https://doi.org/10.1155/2012/215959

Kelley WN. Antihyperuricemic drugs. In: Kelley WN, Harris ED, Ruddy S, Sledge CB, eds. Textbook of Rheumatology. Philadelphia: W. B. Saunders Co; 1991:862-877.

Lee TH, Liu DZ, Hsu FL, Wu WC, Hou WC. Structure-activity relationships of five myricetin galloylglycosides from leaves of Acacia confusa. Bot Stud. 2006;47: 37-43.

Boomsma F, van Dijk J, Bhaggoe UM, Bouhuizen AMB, van den Meiracker AH. Variation in semicarbazide-sensitive amine oxidase activity in plasma and tissues of mammals. Comp Biochem Physiol, C. 2000;126:69-78.