Synthetic Pathway of (3S,7S,8S)-3-((E)-3,4-dihydroxypent-1-en-1-yl)-7,8-dihydroxy-7-methyl-3,4,7,8-tetrahydro-6H-isochromen-6-one

Zidan Yang ； Junjie Xu ； Shangchen Cai

《International Core Journal of Engineering》 7卷6期 (2021/06) Pp. 502-505

https://doi.org/10.6919/ICJE.202106_7(6).0060

摘要

Retrosynthetic analysis was the fundamental and most useful method in determining a synthesis pathway for a compound in organic chemistry. It guided the chemists to observe the connectivity of a molecule, chose a way of disassembling the large molecule into smaller (simpler) ones, and finally figured out the synthesis of those disassembled pieces. We have utilized such method in designing our own synthetic pathway of (3S,7S,8S) -3 -((E) -3, 4 -dihydroxypent-1-en-1-yl) -7, 8 -dihydroxy -7 -methyl -3,4,7,8- tetrahydro-6H-isochromen-6-one. We chose 3-methylcyclohex-2-en-1-one and (R)-3- bromo-2-hydroxypropanal as starting molecules for our pathway. Figure 1 shows the structure of 3-methylcyclohex-2-3n-1-one and Figure 2 shows the structure of (R)-3- bromo-2-hydroxypropanal.

關鍵字

Retrosynthetic Analysis ； Possible Synthetic Pathway ； Potential Advantages and Disadvantages

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