At present, with the mining of deep coal seam, the geological structure conditions are more and more complicated, which makes the processing and interpretation of single geophysical prospecting method more difficult. To solve this problem, a comprehensive advanced detection technology combining TEM and seismic profile method is proposed, that is, seismic profile method is used to detect the structural development in the working face, and TEM method is used to detect the distribution of water-rich abnormal areas in the working face, roof and floor. The possible water-conducting structure and the location of water-rich abnormal area can be accurately detected, and the advanced detection of water inrush disaster can be realized from two aspects.