DMS and DMSO are common volatile organic sulfides. In order to study their degradation products under anaerobic conditions, this paper used DMS and DMSO as fermentation substrates and methanogenic mixed bacteria as strains to carry out Anyang fermentation. The experimental results show that there is no methylotroph methanogens in the fermentation system, and the degradation bacteria are Paraclostridium, Aminobacterium and Desulfovibrio, and the degradation product is hydrogen sulfide.