The paper analyzes the characteristics of smoke spreading in the super‐high atrium of high‐rise buildings and discusses the difficulties in mechanical smoke exhaust fire control design. Taking a high‐rise building as an example, the mechanical smoke exhaust design of its ultra‐high atrium is introduced, and solutions are put forward for its building characteristics, the location of smoke exhaust fan, the value of smoke exhaust volume and the area of the air supply outlet, and corresponding optimization strategies and specific measures are put forward, so that the proposed solution can efficiently remove smoke, achieve the safety purpose of personnel evacuation and reduce the spread of fire.