The skill education of professional courses in higher vocational colleges has important practical significance for the improvement of higher education quality and the training of social professionals. Especially in the face of China's increasing economic aggregate and service demand, the choice of professional curriculum content and education methods in higher vocational colleges, as well as the connection between professional curriculum settings in schools and social needs, determine the future social employment of students, the quality of independent entrepreneurship. From the perspective of social needs, this paper discusses the setting of professional curriculum content and teaching methods in higher vocational colleges, and according to the social industrial structure, employment demand and other external environment development and changes, proposes targeted professional setting and talent training strategies to meet the needs of social comprehensive professional talents.