Diagnostics in Chinese Medicine is a fundamental subject in Traditional Chinese Medicine. The introduction of flipped classroom in the course Diagnostics in Chinese Medicine can remedy the disadvantage in the classical education pattern,as well as enhance students' learning enthusiasm. In this paper, we will elaborate a new teaching pattern, flipped classroom based on MOOC and VR with real‐time interaction and multidisciplinary integration, which provides a new perspective for the innovation of educational pattern in Diagnostics in Chinese Medicine.