Kounis Syndrome (Allergic Angina and Allergic Myocardial Infarction) a Disease to Know: Cases Report and Literature Review

Yong-Ye Yang ； Hung-Yun Su ； Chin-Feng Hsuan ； Kuo-Hsin Lee

《E-Da Medical Journal》 10卷4期 (2023/12) Pp. 52-57

https://doi.org/10.6966/EDMJ.202312_10(4).0006

摘要

Kounis syndrome (KS) is a unique clinical entity that has been defined as acute coronary events resulting from coronary vasospasm, acute plaque rupture, or stent restenosis secondary to allergic or anaphylactic insults. Exposures to numerous allergens such as foods, medications, coronary stents, or environmental factors have been reported to provoke KS. Herein, we described two cases of different types of KS triggered by seafood, epinephrine, and bee sting. These cases highlight the need to not only have a high index of suspicion and early diagnoses of KS but also to be cautious in prescribing medications, particularly epinephrine, beta-blocker, morphine, and nitroglycerin, while managing both cardiac and allergic reactions, without exacerbating the patient's symptoms.

關鍵字

bee stings ； epinephrine ； anaphylaxis ； allergic angina ； kounis syndrome

參考文獻

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