哺乳中母豬經激性腺素或配合前列腺素異構物處理後對誘發懷孕之效應

本研究旨在探討哺乳中母豬應用激性腺素或配合前列腺素異構物（cloprostenol）處理後對誘發懷孕之效應。選用69頭哺乳中母豬分成對照組與四個處理組。對照組母豬不進行內泌素處理，而處理組母豬則以1500 IU／1000 IU或1000 IU／500 IU PMSG（孕馬血清激性腺素）／HCG（人類絨毛膜激性腺素）配合0或180 μg前列腺素異構物處理。PMSG係在母豬哺乳25至30日期間皮下注射，而HCG則在隔80 h後肌肉注射；前列腺素異構物在PMSG處理前24 h採肌肉深處注射。母豬於HCG注射後24 h 與42 h各人工授精一次，其中大部分母豬於授精第1日及其後第7、14、21日分別測定其血漿助孕固酮濃度，供偵測排卵及黃體功能之用。結果顯示，各處理組母豬之分娩間隔日數均較對照組者短（146.0～148.8日vs 158.3日，P＜0.01），而母豬於分娩時及分娩後21日之仔豬頭數及體重則均與對照組者相似。然而，僅用1500 IU PMSG／1000 IU HCG而不用前列腺素異構物處理的母豬分娩率較其餘三處理組或對照組者高（66.7％ vs 45.5～50％或40.0％，P＞0.05），惟未達顯著水準。不過，僅用1000 IU PMSG／500 IU HCG處理之母豬，分娩活窩仔數則呈較低趨勢（P＜0.10），而在授精後第7日與第14日的血漿助孕固酮濃度亦較低（P＜0.05）。母豬經內泌素處理後授精而未懷孕者依其血漿助孕固酮濃度再分成三種型式加以探討，其不育原因仍待深究。綜前所述，僅單獨用1500 IU PMSG／1000 IU HCG在母豬哺乳末期處理後定時授精，可誘發母豬懷孕而較對照組者提高26％分娩率。而且此一技術係在哺乳欄內進行，使母豬同時哺乳與懷孕而縮短分娩間距達10.4日之久，從而改善母豬繁殖效率。

關鍵字

哺乳中母豬；孕馬血清激性腺素；人類絨毛膜激性腺素；前列腺素異構物；定時授精；誘發懷孕

並列摘要

The study was designed to investigate the responses of induced conception after gonadotropins or additional prostaglandin F2α-analog (cloprostenol) treatment in lactating sows. Sixty-nine lactating sows were allotted to control or one of four treatment groups. The control sows received no hormone, while the treated sows were given either 1500 IU/ 1000 IU or 1000 IU/500 IU of pregnant mare serum gonadotropin (PMSG)/ human chorionic gonadotropin (HCG) with or without 180 μg of cloprostenol. The PMSG was given between day 25 and 30 post parturn and HCG was injected intramuscularly eighty hours later to the sow. Cloprostenol was injected deep intramuscularly 24h prior-PMSG treatment. The treated sows were artificially inseminated at 24h and 42h post-HCG injection without detection of estrus. Blood samples were collected from most of the treated sows on the first insemination, and also on days 7, 14 and 21 later for plasma progesterone analysis to monitor the luteal function. The results showed that the treated sows had shorter interval between two successive farrowings than the control ones (146 .0~ 148.8 vs 158.3 days, P ＜0.01) . Additionally, there was no difference (P ＞ 0.05) between the treatment group and control group in litter size and piglet body weight at farrowing and 21 days later. However , the sows given only 1500 IU PMSG/ 1000 IU HCG without cloprostenol had a greater tendency in farrowing rates than those given in the other treatment groups or control group (66.7% vs 45.5 ~ 50% or 40.9%) although no significant difference was observed. On the other hand, the sows treated only with 1000 IU PMSG/500 IU HCG had a lower tendency in the live litter size at farrowing (P ＜0.10), and had lower progesterone concentrations both on days 7 and 14 after insemination (P ＜ 0.05) . Three secretion patterns of progesterone concentration were reclassified and discussed according to the luteal function in the sows that were not pregnant after hormones treatment followed by artificial insemination during lactation. It is concluded that a 26% of farrowing rate could be increased in the lactating sow by only using 1500 IU PMSG/1000 IU HCG treatment followed by fixed-time artificial insemination. Lactation was concurrent with conception and, therefore, the successive farrowing interval was reduced by 10.4 days. The reproductive efficiency could be thus improved in sows.

並列關鍵字

Lactating sow ； Pregnant mare serum gonadotropin ； Human chorionic gonadotropin ； Prostaglandin F2α-analog ； Fixed-time insemination ； Induced conception

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