孕酮與孕馬血清激性腺素重複處理對山羊發情與排卵反應之影響

Estrous and Ovulatory Responses of Does Repeatedly Treated with Progesterone and Pregnant Mare Serum Gonadotropin within One Year

黃政齊(Jan-Chi Huang) ； 楊鎮榮(Jenn-Rong Yang) ； 謝明江(Ming-Chiang Hsieh)

《畜產研究》 34卷2期 (2001/06) Pp. 141-149

摘要

本試驗之目的在探討母山羊在一年之內接受不同間隔與次數之孕酮（progesterone）與孕馬血清激性腺素（PMSG）重複處理後，對其發情與排卵反應是否有不良影響，以做為未來改善誘發季節性乏情母羊之發情與發情同期化之參考。試驗選用生殖能力正常之母山羊40頭逢機分為4組，於一年內分別依下列4種不同間隔與次數接受孕酮與PMSG之處理：（i）第0、42、72、102及360天，計處理5次。（ii）第0、72、102及360天，計處理4次。（iii）第0、102及360天，計處理3次。（iv）第0、360天，計處理2次。各組於處理後觀察母山羊發情起始與持續時間，並於發情後第6～7日以外科手術檢視其卵巢狀態，以瞭解各種不同處理間隔與次數對母山羊繁殖性能之影響。試驗結果顯示，以孕酮與孕馬血清激性腺素重複處理之羊隻，第102天之內重複3次以上處理，或於第102天時進行第2、3及第4次處理，雖對羊隻發情率影響不大，但處理後發情起始之時間有明顯延遲之現象，且降低發情母羊中有排卵者所佔之比例及排卵數。發情後第6日以腹中線剖腹術檢視卵巢狀態，3 mm以上之濾泡數及早期萎縮之黃體數，在不同處理次數間或不同處理間隔之間均無明顯之差異。由以上結果顯示，母山羊在一年之內以孕酮與PMSG進行3次以上處理，或於第102天時進行第2、3或第4次重複處理時，顯著延遲母山羊發情起始之時間、排卵母羊比例及排卵數而影響母山羊之生殖效率，但第一年內在第102天之前重複處理2至4次，並不影響母山羊於第360天再重複處理時之生殖表現。

關鍵字

山羊 ； 孕酮 ； 孕馬血清激性腺素 ； 發情 ； 排卵

並列摘要

This experiment was conducted to examine the effects of repeated treatment of progesterone and pregnant mare serum gonadotropin (PMSG) within one year on the estrous and the ovulatory responses of goat does. Forty does of Nubian crosses without experiencing any previous treatment of PMSG were randomly divided into 4 groups and were assigned to receive one of following progesterone and PMSG treatment regimes respectively within one year: (i) on day 0, 42, 72, 102 and day 360, totally 5 times, (ii) on day 0, 72, 102 and day 360, totally 4 times, (iii) on day 0, 102 and day 360, totally 3 times, and (iv) on day 0 and day 360, twice a year . Estrus was induced and synchronized by administration of 125 μg of PGF_2 α and 500 IU of PMSG on day 9 of an 11-day progesterone treatment. The initiation time of estrus in does treated for over 3 times within day 102 was significantly delayed, and the percentage of ovulated does and the number of corpus lutea were lower than that of animals treated on the rest day and times. However, no significant effect on ovulatory response was observed when the does were treated again on day 360 irrespective the times of PMSG treatment within day 102. No significant difference in the number of follicles ( ＞ 3 mm) and premature regressed corpus lutea existed between any treatments. These results indicated that the frequency of PMSG treatment was positively correlated to the time interval from PG administration to estrus initiation and lower the ovulation incidence and the ovulation rate. Does repeatedly treated with PMSG on day 360 irrespective the times being treated before day 102 in the first year of estrus induction showed normal reproductive performance.

並列關鍵字

Goat ； Progestagen ； PMSG ； Estrus ； Ovulation