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Research Progress on Pathogenesis and Treatment of Cancer - related Fatigue

摘要


Cancer-related fatigue (CRF) is one of the most painful symptoms of cancer patients, and the specific pathogenesis of the disease is not known, and may be related to gene expression and signal transmission, skeletal muscle and mitochondrial abnormalities, inflammatory response and immune disorders, cancer itself and its treatment and others. Clinically, non-drug therapy is the main treatment, and traditional Chinese medicine (TCM) has a certain advantage in the treatment of CRF. This article will summarize the possible pathogenesis of CRF and the treatment of traditional Chinese and western medicine in recent years.

參考文獻


Berger AM, Mooney K, Alvarez-Perez A et al. Cancer-Related Fatigue, Version 2.2015. J Natl Compr Canc Netw. 2015;13(8):1012-39.
Bower JE. The role of neuro-immune interactions in cancer-related fatigue: Biobehavioral risk factors and mechanisms. Cancer-Am Cancer Soc. 2019;125(3):353-364.
Gonzalez VJ, Abbas-Aghababazadeh F, Fridley BL, Ghansah T, Saligan LN. Expression of Sestrin Genes in Radiotherapy for Prostate Cancer and Its Association With Fatigue: A Proof-of-Concept Study. Biol Res Nurs. 2018;20(2):218-226.
Hashemi S, Fernandez MJ, Saligan L, Sonis S. Exploring Genetic Attributions Underlying Radiotherapy-Induced Fatigue in Prostate Cancer Patients. J Pain Symptom Manage. 2017;54(3):326-339.
Ouyang X, Zhang G, Pan H, Huang J. Susceptibility and severity of cancer-related fatigue in colorectal cancer patients is associated with SLC6A4 gene single nucleotide polymorphism rs25531 A>G genotype. Eur J Oncol Nurs. 2018;33:97-101.

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