The porous polysulfone membrane was used as the support body, and a molecularly imprinted polymer composite layer with evodiamine as the template molecule was coated on the surface of the polysulfone membrane by sol-gel method. It was found that the blending solution of methanol solution and tetrahydrofuran solution with a volume ratio of 5:1 as the solvent could satisfy the process conditions of sol-gel imprinting reaction without affecting the structure of polysulfone membrane. Infrared testing of the composite membrane and the molecularly imprinted polymer powder proved that the imprinted polymer could be attached to the supporting membrane. Then the surface morphology and structure of the prepared molecularly imprinted composite membrane were characterized by a scanning electron microscope. It can be clearly observed that the surface of the supporting membrane was covered by a layer of sol-gel molecularly imprinted polymer. The flux of evodiamine molecularly imprinted composite membrane was measured at 0.4 MPa at room temperature, and it was found that the flux reached 19.80 L.m^(-2).h^(-1).