快速現場評估在超聲引導下支氣管內鏡針吸活檢的應用價值

目的：分析快速現場評估（rapid on-site evaluation, ROSE）在支氣管內鏡超聲引導下經支氣管針吸活檢（endobronchial ultrasound-guided transbronchial needle aspiration, EBUS-TBNA）的應用效果。方法：對本院2015～2020年行EBUS-TBNAROSE病例進行回顧性分析。結果：共收集221份標本，合適診斷有212份（95.9%），其中淋巴結病灶182枚，非淋巴結病灶39份。總體明確診斷率為87.3%。其中206份有做細胞塊，104份有做免疫組化，40份有做EGFR基因檢測。非淋巴結病灶確診率（31份，79.5%）與淋巴結的確診率（162份，89%）在統計學上無顯著性意義（χ^2=1.84,P>0.05）。結論：ROSE能即時提供EBUS-TBNA結果，協助病變診斷、分期，還可為癌症患者個體化治療提供分子免疫學依據。

關鍵字

支氣管內鏡；超聲引導下經支氣管針吸活檢；快速現場評估；肺癌

並列摘要

Objective: To analysis the effect of rapid on-site pathologic evaluation on endobronchial ultrasound-guided transbronchial needle aspiration. Methods: A retrospective study of ROSE cases with pathology staff participating in EBUS-TBNA in our hospital from 2015 to 2020. Results: A total of 221 cases were collected, and 212 cases (95.9%) were diagnosed, in which 39 cases were non-lymph node lesions, and 182 cases were lymph node lesions. The overall diagnostic rate was 87.3%. Among all cases, 206 cases were made into cell blocks, 104 cases performed immunohistochemistry, and 40 cases performed EGFR gene detection. There was no statistical significance between the differences of diagnosis rate in non-lymph node lesions (31 cases, 79.5%) and lymph node lesions (162 cases, 89%) (X^2=1.84, P>0.05). Conclusion: ROSE can provide immediate EBUS-TBNA evaluation, which can not only assists in diagnosis and staging but also provides further auxiliary molecular immunology basis for individualized therapy of patients with cancers.

並列關鍵字

Lung cancer ； Endobronchial ； Ultrasound-guided transbronchial needle aspiration ； ROSE

主題瀏覽