酒精依賴患者之決策缺失特性

酒精使用與衝動選擇有關。酒精依賴者持續飲酒而未能顧及負向後果，其上癮行為反映出執行功能上的缺失。本研究目標在於澄清酒精依賴者之決策功能。我們比較了19名酒精依賴患者與24名年齡配對的健康成年人在愛荷華賭局作業的表現。結果顯示，相較於正常組，酒精依賴患者在在愛荷華賭局作業有較多不利後果之選擇，且愛荷華賭局的整體表現較差。本研究結果指出大多數的酒精依賴患者在以情緒為基礎的學習上是有缺失的。本研究結果可協助用來設計相關之治療介入計劃。

關鍵字

酒棈依賴；決策；執行功能；衝動

並列摘要

Alcohol use is often associated with impulsive choices. Alcohol dependents also exhibit deficits in executive functions as reflected by their persistent alcohol use despite of adverse consequences. The aim of this study was to clarify the decision-making functioning in alcohol-dependent patients. We compared 19 alcohol-dependent (AD) patients with 24 age-matched healthy controls on the performance of the Iowa Gambling Task (IGT). In comparison to healthy controls, the AD group made more disadvantageous choices and had a poorer performance on the IGT. These results suggest that deficits related to emotion-based learning exist in AD patients. These results may have important implications for designing treatment programs.

並列關鍵字

alcohol dependence ； decision making ； executive function ； impulsivity

參考文獻

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Balodis, I. M., MacDonald, T. K., & Olmstead, M. C. (2006). Instructional cues modify performance on the Iowa Gambling Task. Brain Cogn, 60(2), 109-117.

Barry, D., & Petry, N. M. (2008). Predictors of decision-making on the Iowa Gambling Task: independent effects of lifetime history of substance use disorders and performance on the Trail Making Test. Brain Cogn, 66(3), 243-252.

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酒精依賴患者之決策缺失特性

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