台灣扁柏皮部之化學成分研究

Studies on the constituents of the bark of Chamaecyparis obtusa var. formosana

柯建民(Chien-Ming Ko)

指導教授 ： 郭悅雄

國立臺灣大學/理學院/化學研究所/碩士(2005年)

https://doi.org/10.6342/NTU.2005.00315

摘要

台灣扁柏(Chamaecyparis obtusa var. formosana)，又名黃檜或厚殼（以其樹皮較紅檜厚而得名），特產於海拔1500公尺至2500公尺的雲霧帶，且大部份分佈在中部以北的地區，馬告國家公園即是台灣扁柏林最集中的地方。其木材有辣味、具芳香、且具高度耐朽抗蟲性。我所分析的台灣扁柏皮部，以丙酮浸泡得到萃取物之後，運用矽膠薄層分析、高效液相層析儀及再結晶等方式進行下一步的分離純化。純化後的化合物在測得氫核磁共振圖譜、碳核磁共振圖譜、紅外線光譜與質譜後，推測其結構，若推測的結構經化學資料庫MDL Crossfire Commander和SciFinder Scholar查詢為已知化合物者，則與文獻值比對確定其結構。若是新化合物，則依需要進行二維核磁共振圖譜實驗確定其結構。

本實驗共鑑定得到45個化合物，分別為:
一、單萜類(Ｍonoterpenoids) 化合物 1個
二、倍半萜類(Sesquiterpenoids) 化合物2個
三、雙萜類(Ｄiterpenoids) 化合物35個
四、固醇類(Steroids) 化合物1個
五、雙聚類(Dimers) 化合物5個
六、其它類(Others) 化合物1個
其中8個為新化合物。

關鍵字

扁柏 ； 皮部

並列摘要

Chamaecyparis obtusa var. formosana (bark) is indigenous in the central and north part of Taiwan at altitudes of 1500~2500 meters. The wood of this tree is the best building material in Taiwan.
The acetone extract from the bark of C. obtusa var. formosana was concentrated to give a residue, which was separated by column chromatography on silica gel, preparative thin layer chromatography and high performance liquid chromatography (HPLC) to give forty-five compounds. Of these compounds, eight of them are new compounds. Among the isolated components, there are one monoterpenoid, two sesquiterpenoids, thirty-five diterpenoids, five dimers, one steroid, the other one do not belong to any of the above categories.
The known compounds were identified by spectral analysis and compared with those reported in literatures or authentic samples. The structures of new compounds were elucidated by spectral evidence including one-dimension and two-dimension spetral analysis.

並列關鍵字

Chamaecyparis obtusa var. formosana ； bark

參考文獻

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