探討酵母菌核糖核酸結合蛋白Rbp1p對絲狀生長中多種基因之轉譯調控

Characterization of Rbp1p-mediated translation of variegated genes in yeast filamentous growth

彭康禹(Kang-Yu Peng)

指導教授 ： 李芳仁

國立臺灣大學/醫學院/分子醫學研究所/碩士(2015年)

https://doi.org/10.6342/NTU.2015.10529

摘要

酵母菌核醣核酸結合蛋白Rbp1最初被發現為會負向調控生長的因子。其在結構上包含三個核醣核酸識別序列(RRM)和兩個富含麩氨酸區域，並且在碳端具有一個富含天門冬氨酸、甲硫胺酸和脯胺酸的區域。實驗室之前研究已經發現在

關鍵字

核糖核酸結合蛋白 ； 酵母菌 ； 轉譯 ； 菌絲生長 ； 轉錄因子

並列摘要

Rbp1, as a RNA binding protein, was first identified as a negative growth regulator in Saccharomyces cerevisiae. Rbp1 contains three RNA recognition motif (RRM), two glutamine-rich regions, and asparagine-methionine-proline-rich (NMP) region in the C terminus. Our previous studies have shown that deletion of RBP1 resulting in a hyper ager-invasive growth in

並列關鍵字

Rbp1 ； yeast ； translation ； filamentous growth ； transcription factor

參考文獻

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