新穎的急性跟腱斷裂微創手術評估

Evaluation of a Novel Minimally Invasive Surgery for Acute Achilles Tendon Rupture: Tendon Healing and Biomechanical Properties

蔡易霖(I-Lin Tsai)

指導教授 ： 李財坤

國立臺灣大學/醫學院/國際三校農業生技與健康醫療碩士學位學程/碩士(2020年)

https://doi.org/10.6342/NTU202003356

摘要

急性跟腱斷裂好發於運動員及假日從事休閒運動的中年人。然而隨著年齡的增長，在跟腱斷裂的風險下，老年人的血液循環降低和組織沾黏的機會增加對於病患復原是一大挑戰。微創手術已成為一種趨勢。由於傷口較小，恢復和康復時間較短，因此患者可以在更短的時間內恢復原來的生活方式。透過國際三校學程的引薦，我與骨科醫師進行合作，開發新型跟腱微創手術，其中包含臨床上的應用及市場推廣。在與台灣，日本和法國的10多位骨科醫生進行訪談之後，大多數的醫師對於跟腱微創手術肌腱的生物力學特性及復原效果提出疑問。先前的大體研究僅能說明縫合方法的機械強度，而無法對肌腱癒合的過程和恢復後進行有效分析。因此，這份統整性報告將主要側重於新型超音波導引跟腱微創手術的介紹，以及將產品商化、創新創業實務的想法，包括市場規模，商業模型和市場策略。此外，將融合兩年碩士所學，提出有關促進肌腱癒合和生物力學性能測試的相應實驗設計。

關鍵字

急性跟腱斷裂 ； 微創手術

並列摘要

Acute Achilles tendon ruptures often occur in athletes and middle-age people involving in recreational sports. However, with the increase of aging, decreased blood flow and increased tissue stiffness may jeopardize elders under the risk of Achilles tendon rupture. Minimally invasive surgery has become a trend. With less wound size and shorter recovery and rehabilitation time, patients could return to the original lifestyle in a shorter period. With the support of GIP-TRIAD, I had a priceless opportunity to collaborate with Taiwanese orthopedic surgeon and develop a minimally invasive surgery for Achilles tendon rupture. However, after interviewing with more than 10 orthopedic surgeons among Taiwan, Japan, and France, most of them are concerning the biomechanical properties and the rehabilitation procedure regarding minimally invasive surgery. The previous Cadaver studies could only explain the mechanical strength of suture methods but couldn’t validate the process of tendon healing and the post-recovery analysis. Therefore, this comprehensive report will be mainly focusing on introducing a novel ultrasound-guidance minimally invasive surgery for Achilles tendon rupture, the idea of creating a new business including the market size, business model, and the market strategy. In addition, a corresponding scientific pre-proposal regarding the acceleration of tendon healing and the biomechanical properties test will be displayed.

並列關鍵字

Acute Achilles Tendon Rupture ； Minimally invasive surgery

參考文獻

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