The primary objective of our research was to explore the biotechnology environment in Taiwan and do qualitative valuation analysis of two biotech companies in Taiwan one with approved product on the market and the other one without in order to analyze the decision pattern for investment. By applying the qualitative valuation analysis tool, adopted from the book The Biotech Investor’s Bible written by George Wolff, and five-star score system we found that the value of the company does not come only with the product on the market, specifically this value comes from the market’s trust of the drug development pipeline and management of the company. Based on our results, we also see that biotech stocks are very dynamic. These stocks follow the global and local market behavior. Also, they have their own dynamics related to the drug development pipeline, corporate news, and regulatory environment. Market expectations and unfulfilled expectations have huge impact on the biotech company stocks. In order to make investment decision, all these factors should be taken into account. Although a reasonable broad research was conducted for these two companies, our research data is limited to generalize this research to whole biotech environment in Taiwan due to the limited number of companies analyzed. This suggests that in order to generalize this justification further analysis with broader number of companies must be conducted. Discoveries of our research clearly reveal the importance of the eight factors discussed in this study to analyze the value of biotech companies for investment. It may also help, in particular with Taiwanese biotech companies, to assess their strategy in relation to improve their credibility and market capitalization with analysis in these eight factors. Finally, the results may also help the investors who would like to improve their biotechnology company portfolios.