以電滲經絡理論模擬探討針刺的動力行為

On an electro-osmotic meridian theory for numerically exploring dynamical behavior of acupuncture

黃金龍(Chin-Long Huang)

指導教授 ： 許文翰

國立臺灣大學/工學院/工程科學及海洋工程學研究所/博士(2007年)

https://doi.org/10.6342/NTU.2007.01046

摘要

中 文 摘 要

經絡及針灸在中國傳統醫學一直扮演著理論核心的角色。二千年前，「黃帝內經」已詳述了一些客觀的事實，而在生理解剖及顯像科技發達的今日，卻無法清楚地敘述經絡的生理特性，使得經絡理論依舊蒙著一層神秘的面紗。本研究嘗試從力學的觀點將經絡生理與氣血運行的非線性交互作用作一具體的機制描繪。人體經絡線中，膽經與胃經是于小腿段處較深層骨間膜的腓側和脛側，它們沿著經絡線的微血管呈現節段性的分佈，由於微血管密集之處與穴位點的位置吻合，故將其作為研究的主題。本研究透過科學模式的建立並利用數值模擬的方式求解不具壓縮性的定常牛頓流體電滲流運動的方程組，此外亦將滲透係數列入考慮，藉以模擬微血管壁所扮演的角色及嘗試解釋複雜的經絡生理現象。此外，藉由引入合理的邊界條件與生理參數，由研究的結果得知于經絡線上的流速與文獻中所述的小分子循經遷移速度相符。當改變血管壁的滲透係數與動脈端的血壓時，于經絡線上活動的組織液，其速度將對應地發生改變，這符合針刺穴道時所引發的生理反應。若改變組織液(經絡線)的靜壓與入流的條件，可詮釋「氣滯血淤」與「氣行血亦行」的中醫理論。此外，經絡為一電滲流流場，電滲流可因動量方程式中電力項之存在，使得電滲流的邊界層比同物理參數的層流還薄，這有助於低雷諾數組織液的動量傳輸。透過本文所採用的電滲經絡物理模型，可清楚的解析氣血交換的現象，同時亦可解釋當針刺時，肥大細胞脫顆粒所引發穴位高電位與經絡電波與電流傳導的現象，這些結果有助于進一步了解針刺與電針治療的功能與物理機制。

關鍵字

經絡 ； 穴道 ； 電滲流 ； 肥大細胞脫顆粒 ； 數值模擬 ； 氣血循環動力模型

並列摘要

Abstract:
A numerical study has been performed on the proposed bio-fluid dynamics model to explore some major human meridian characteristics in Chinese medicine. The proposed meridian model involves tissue fluids, which contain ions and nutrition, in the meridian passage. The tissue fluid under investigation can interact with the blood in the capillary vessel at the acupuncture points through a complex electro-osmosis transport process occurring in the meridian path. The investigated physical domain consists of a meridian path with three acupuncture points, namely, GB 37, 38, 39, which are connected with their associated small meridian bodies (SMBs). Based on the properly chosen physiological coefficients, the simulated mean tissue fluid velocity has been shown to have a magnitude of 3.37cm/min (3D model result). This magnitude is observed to be increased and decreased with the hydraulic pressure of the arteriole with the maximum and minimum values of 4.34 cm/min (3D model result) and 2.40 cm/min (3D model result), respectively. Our simulated results are in good agreement with the experimental findings reported in the literature. In the meridian, both blood and tissue fluid flows exhibited complex electro-osmosis nonlinear behaviour. The immediate response due to an externally applied acupuncture is analyzed to reveal the elliptic meridian nature, which is intrinsic in the body fluid. The interaction between the body fluid and blood flow as the master and mother, and the influence of the blood circulation on the meridian system and vice versa are also analyzed in detail. Furthermore, meridian is considered as a passage to proceed the electroosmosis transport. Due to the influence of electric term in the momentum equation, the boundary layer thickness is thinner than the common laminar flow under the same physical coefficients. Through this electroosmosis transport flow model, the phenomena of Chi-blood interaction can be revealed in detail. During acupuncture, how the mast cell degranulation can result in meridian high voltage and transport of electric wave and current has been properly translated by this model. The predicted results are useful for revealing the physical mechanism in acupuncture and electric-acupuncture treatments.

並列關鍵字

meridian model ； tissue fluids ； acupuncture points ； mast cell degranulation ； electro-osmosis transport

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