聚(氮-異丙基丙烯醯胺)衍生溫度感應性共聚微乳膠之低臨界溶液溫度之研究

Research of the LCST of Poly-(N-isopropylacrylamide) Related Thermoresponsive Copolymer Microgels:

楊恩伉(En-Kang Yang)

指導教授 ： 邱文英

國立臺灣大學/工學院/材料科學與工程學研究所/碩士(2006年)

https://doi.org/10.6342/NTU.2006.01040

摘要

本研究的目的在於製備以聚-氮-異丙基丙烯醯胺(poly-NIPAAm) 為主體衍生之次微米級溫度感應性微乳膠，並探討其性質及應用。以無乳化劑之乳化聚合法，合成粒徑約200~500nm之共聚微乳膠，討論共聚單體的種類及組成對於反應速率、粒徑顆粒型態及其溫度感應性質的影響。
已知poly-NIPAAm在LCST(Lower Critical Solution Temperature)溫度之下會呈親水狀態，在LCST 溫度以上會呈疏水狀態，其LCST約在32℃。若在聚合過程中加入疏水性單體甲基丙烯酸丁酯(BMA)，可使所形成的高分子具有較低的LCST溫度；若加入疏水性單體丙烯酸丁酯(BA)，可使LCST降得更低。並經由TEM和各種熱性質測定證實，兩者已形成random copolymer。高分子水溶液的溫度敏感型行為，亦可以熱力學理論模型模擬之。

關鍵字

氮-異丙基丙烯醯胺 ； 低臨界溶液溫度 ； 甲基丙烯酸丁酯 ； 丙烯酸丁酯

並列摘要

The goal of the research is the preparation of poly-N-isopropylacrylamide (p-NIPAAm) related thermoresponsive copolymer microgels and discussions of their properties and application. The thermoresponsive copolymer latex particles with the average diameter of about 200~500nm were prepared via surfactant–free emulsion polymerization. The effects of co-monomers and composition on the synthesis, kinetics, particle size, morphology, and thermoresponsive properties of the copolymer latex were studied to realize the relationship between the synthesis condition, the particle morphology and thermoresponsive properties successfully. Now we find that if we add a small amount of hydrophobic monomer, BMA, into NIPAAm monomer to copolymerize, the resulting polymer will have a decreased LCST. If we add a small amount of BA, into NIPAAm monomer to copolymerize, the resulting polymer will have a more decreased LCST. In addition, the thermodynamic model can be used to describe the thermoresponsive behavior of the polymer solution.

並列關鍵字

NIPAAm ； BMA ； BA ； LCST

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