應用於DNA解煉曲線分析的高效互動式粒子追蹤方法

An Effective & Interactive Approach to Particle Tracking for DNA Melting Curve Analysis

李穎忠(Weng Chong Lei)

指導教授 ： 張智星

國立臺灣大學/電機資訊學院/資訊工程學研究所/碩士(2015年)

https://doi.org/10.6342/NTU.2015.01764

摘要

DNA解煉曲線分析是一種研究DNA序列變異的重要技術，但是研究人員必須標記螢光顯微鏡拍下的實驗影片才能得到實驗數據，這是一個很花時間的工作。本論文提出一個互動式的影片標記系統，這系統利用粒子追蹤方法自動替使用者標記實驗影片，並設有互動機制，讓使用者只需要標記一小部分，就可以完成整個標記工作。我們的系統經過實驗驗證其有效性。

關鍵字

DNA解煉曲線分析 ； 影片標記 ； 粒子追蹤

並列摘要

DNA melting curve analysis is an important technique for the detection of DNA sequence variants. However, it requires object annotation in video from fluorescence microscopy, which is tedious. In this thesis, we present an interactive video annotation system that tracks the particles in video interactively and provides all the labels with little manual effort. Evaluations on realistic video data demonstrate the effectiveness of our system.

並列關鍵字

DNA melting curve analysis ； Video annotation ； Particle tracking

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