新世代磁振造影技術：高時空解析度寬頻磁振造影

Next generation MRI:High Spatial/Temporal Resolution Imaging with Wideband MRI

吳億澤(Edzer Lienson Wu)

指導教授 ： 陳志宏

共同指導教授 ： 林啟萬(Chii-Wann Lin)

國立臺灣大學/工學院/醫學工程學研究所/博士(2015年)

https://doi.org/10.6342/NTU.2015.10856

摘要

無資料

關鍵字

時空間解析度 ； 寬頻 ； 磁振造影

並列摘要

Despite years of development, magnetic resonance imaging (MRI) continues to suffer from the limitations of long scanning time and low resolution, when compared to computer tomography (CT) technology. Ranked among the most important medical imaging technologies, MRI provides abundant anatomical information as well as physiological in vivo data, revealing microscopic as well as macroscopic features of biological tissue. To meet the increasing demand of such a versatile imaging modality, various methods of accelerating MRI have been developed over the past several decades.
In this study, we propose two types of Wideband MRI techniques as a means of significantly increasing the speed of both 2D 3D MR imaging process. We have investigated the theoretical underpinnings of these techniques and proposed methods to enhance image-qualities. Through sequence design and adequate signal processing, accelerated 2D 3D images can be obtained without compromise.
Routine usage of Wideband MRI can reduce scan times to between 1/2 and 1/8 the time currently required. From real-time biological information to functional imaging, the improved temporal/spatial resolution provided by Wideband MRI technology enables a wide variety of applications never before envisioned, and paves the way for fast whole-body early-stage cancer screening in the near future. Shorter scanning times with Wideband MRI would undoubtedly improve patient experience in MR screening. More importantly, Wideband MRI could increase patient throughput, providing significant financial benefits for the health industry around the world.

並列關鍵字

spatial/temporal resolution ； Wideband ； simultaneous multi-slice ； phase encoding

參考文獻

P.C. Lauterbur, "Image formation by induced local interactions. Examples employing nuclear magnetic resonance. 1973," Clin Orthop Relat Res, 3-6 (1989).

2 K.P. Pruessmann, M. Weiger, M.B. Scheidegger, P. Boesiger, "SENSE: sensitivity encoding for fast MRI," Magn Reson Med 42, 952-962 (1999).

3 M.A. Griswold, P.M. Jakob, R.M. Heidemann, M. Nittka, V. Jellus, J. Wang, B. Kiefer, A. Haase, "Generalized autocalibrating partially parallel acquisitions (GRAPPA)," Magn Reson Med 47, 1202-1210 (2002).

4 M. Lustig, D. Donoho, J.M. Pauly, "Sparse MRI: The application of compressed sensing for rapid MR imaging," Magn Reson Med 58, 1182-1195 (2007).

5 S. Mori, M. Endo, T. Tsunoo, S. Kandatsu, S. Tanada, H. Aradate, Y. Saito, H. Miyazaki, K. Satoh, S. Matsushita, M. Kusakabe, "Physical performance evaluation of a 256-slice CT-scanner for four-dimensional imaging," Med Phys 31, 1348-1356 (2004).