The information technology is highly developed nowadays. It is also used as a new tool for creating the contents. Combining information technology with multimedia can bring us innovative and value-added digital contents for multimedia industries. In this thesis, we will propose and implement an interactive multimedia system, virtual piano system, which integrates information technology with interactive multimedia contents. This research’s motivation is based on a concept originally derived from the digital musical instrument and music toys. In this thesis, we use a video camera to capture the movements of user’s fingertips. After detecting and analyzing the movement, the corresponding piano sound will be played in real-time. Digital image processing and MIDI technology are involved in this study. It has many potential capabilities for developing products for digital content industries such as interactive game and portable digital learning device.