The goal of this thesis is preparing discotic liquid crystals exhibiting helical columnar supramolecular structures. In the first part, a helicene compound based on hexabenzocoronene (HBC) has been synthesized. Incorporation of the helical conformation onto the HBC has imposed a more ordered intracolumnar molecular packing than the reported planar HBC analogues. In the other part, a series of hexakis(phenylethynyl)benzene derivatives with chiral side-chains have been synthesized and studied. All compounds showed a columnar rectangular liquid crystalline phase within wide temperature ranges by differential scanning calorimetry, polarizing optical microscopy, and powder X-ray diffraction studies. Intramolecularly, the chiral chains of one side-arm have influenced the other five sidearms to induce a helical molecular conformation. Furthermore, intermolecularly, helical columns from propeller-like compounds were generated. Chiroptical studies by circular dichroism (CD) in liquid crystalline phases and scanning tunneling microscopy at liquid-solid interface confirmed intramolecular and intermolecular chiral inductions. Chiral induction by doping a chiral discogen into an achiral analogue was confirmed by increased CD signal intensity upon doping.