以陽極氧化鋁/二氧化鈦球伴隨奈米銀粒子應用於表面增強拉曼散射基板之製作

Anodic aluminum oxide / titanium dioxide spheres with silver nanoparticles for the production of surface-enhanced Raman scattering substrates

劉育如(Yu-Ju Liu)

指導教授 ： 許世杰

淡江大學/工學院/化學工程與材料工程學系碩士班/碩士(2022年)

https://doi.org/10.6846/TKU.2022.00791

摘要

近年，表面增強拉曼散射基板越來越廣泛應用於各個領域之中，諸如生物感測器、食品安全衛生、法醫檢驗、古文物鑑定等，因此研究良好的SERS基板受到各界的重點關注。製備SERS基板有幾項要點，具有大量且分佈均勻的熱點、能夠良好抓取分析物、高靈敏性增強效果。
文獻中利用光刻、壓印等方法為基底，以表面自組裝單分子膜抓取相對應待測的方式製備SERS基板，雖有良好的陣列化奈米結構，但是會有成本過高、檢測物質單一化、SERS效果減弱等問題。本團隊先前報導中提出將市售的印刷電極片利用電化學法，在形成金屬奈米顆粒的同時電吸附檢測分子，達到基板檢測多相物質的設計，然而電化學法生成的奈米結構均勻性不佳，導致再現性較低的問題。
本研究提出使用製備容易的陽極氧化鋁為基底，搭配具有良好吸附檢測物的二氧化鈦球伴隨銀奈米顆粒，製做出能改善傳統系統檢測物單一與電吸附法均勻性不佳的SERS基板。

關鍵字

表面增強拉曼散射技術 ； 陽極氧化鋁 ； 二氧化鈦奈米球 ； 銀奈米顆粒 ； SERS基板 ； 自組裝

並列摘要

Recently, the surface-enhanced Raman scattering substrates have become more and more widely used in various fields. Such as biosensors, food safety, forensic science, Scientific Identification of Antiques, etc. Therefore, There has caught the attention of scholar how to fabrication of sensitivity SERS substrates. There are several key points for preparing SERS substrates, including the surface has uniform and a large number of hot spots, good capture of analytes, and high enhancement.
In the literature, they usually use photolithography, embossing and other methods to prepare the SERS substrate. Furthermore, self-assembled monolayer above the mental to caught analytes. Although it has a good arrayed nanostructure, it will have high cost. The SERS effect may will be weak because this SAM monolayer. In our previous report, the team proposed to roughness the gold surface of the commercially available screen printed electrodes by electrochemical. The surface will be formed nanoparticles and electro-sorption detection molecules to achieve of detecting diverse substances by the same system substrate. However, the nanostructures generated by electrochemical methods are so uniform poorly that it can’t reproducibility.
In our study, it is proposed to use easily prepared anodic aluminum oxide as the substrate. The titanium dioxide spheres has good adsorption of the analytes. The silver nanoparticles has most excellent enhance effect. So, the research will study to prepare AAO/TiO2/Ag substrate. That can improve the single detection of the traditional system and the poor uniformity of the electrosorption method.

並列關鍵字

Surface-enhanced Raman spectroscopy ； AAO ； Ag NP ； TiO2 ； SERS substrate ； Self-assembled

參考文獻

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