補充葉黃素複方飲對保護眼睛效果之研究

Effect of lutein complex drink on protecting eyes

廖惠茹(Hui-Jui Liao)

指導教授 ： 王進崑

中山醫學大學/健康管理學院/營養學研究所/碩士(2014年)

https://doi.org/10.6834/CSMU.2014.00108

摘要

現代人長期處於高壓力環境，加上長時間的注視電腦、手機、平板，使得用眼過度，衍生出許多眼睛健康問題。葉黃素是重要的天然抗氧化劑，能保護細胞免受自由基傷害，並且可過濾90%以上的藍光波長光線，可避免眼睛受傷害。本研究擬探討飲用葉黃素複方飲對於眼睛保護、視力改善及抗氧化之功效。以近視、眼睛疲勞、用眼過度的健康人作為介入對象，共56位受試者參與。本試驗之試驗期共五個月，試驗期結束後的一個月為追蹤期。受試者每天飲用一瓶的試驗樣品(每瓶60ml)。試驗前後及追蹤期分別進行體位測量及採集血液檢體，每個月測驗視力並進行眼睛功能性評估。結果顯示，連續服用葉黃素複方飲五個月後，在眼睛舒適度、最佳矯正視力、對比敏感度、眼睛調節能力、立體視力、眼壓測試、光干擾測試、眼底黃斑部密度及乾眼測試等皆有正面的改善；在血液生化方面，飲用後顯著調降血漿中脂質過氧化物(TBARS)、全血自由基及血清中HS-CRP濃度。本研究證實葉黃素複方飲具有保護眼睛、視力改善及抗氧化之功效。

關鍵字

葉黃素 ； 用眼過度 ； 視力改善 ； 自由基 ； 抗氧化

並列摘要

Modern has high stress in life. Long time using computers, mobile phones and tablet PC make eyes overuse. Lutein is an important natural antioxidant that can protect cells from free radical damage.Lu also can filter out more than 90% of blue light, which may cause eye injuries.

This study was focused on the eye protection by using lutein complex drink. The improvement in visual acuity and antioxidation to myopia and eye fatigue were evaluated from the healthy people who have the problem of overused eyes. Total 56 subjects were completely involved in this study. Each subject drank lutein complex drink (60ml/day) for continuous five month. And one month after the stop of experiment period was the follow-up period. Subjects were conducted to anthropometry and their blood samples were collected during the trial period and follow-up period, the visual acuity and eyes function were also assessed every month.

After five months of lutein complex drinking, positive improvement on eye protection and visual acuity, including eyes comfort level, best-corrected visual acuity, contrast sensitivity, amplitude of accommodation, stereopsis, intraocular pressure, photo stress time, macular pigment optical density and dry eye status. In addition, the TBARS values of plasma and the concentrations of HS-CRP and whole blood free radical were also significantly reduced.

In conclusion, lutein complex drink could contribute to eye protection and showed great improvement on visual acuity and antioxidation.

並列關鍵字

lutein ； overuse of eyes ； improvement of visual acuity ； free radical ； antioxidation

參考文獻

Ma, L., Lin, X.-M., Xu, X.-R., Zou, Z.-Y., Wang, Z.-X., Huang, Y.-M., & Li, Y. (2009). Serum lutein and its dynamic changes during supplementation with lutein in Chinese subjects. Asia Pac J Clin Nutr 18, 318.

章清,沈新南,姚國英and 吳岷(2008). Effect of lutein on renal injury in alloxan induced diabetic rats. 營養學報, 388-391.

Anderson, H. A., Hentz, G., Glasser, A., Stuebing, K. K., and Manny, R. E. (2008). Minus-lens-stimulated accommodative amplitude decreases sigmoidally with age: a study of objectively measured accommodative amplitudes from age 3. Invest Ophthalmol Vis Sci 49, 2919-2926.

Bachorik, P. S., and Ross, J. W., (1995). National cholesterol education program recommendations for measurement of low-density lipoprotein cholesterol: executive summary. The National Cholesterol Education

Bone, R. A., & Landrum, J. T. (2010). Dose-dependent response of serum lutein and macular pigment optical density to supplementation with lutein esters. Arch Biochem Biophys 504, 50-55.