新陳代謝症候群相關因素盛行率之描述性研究

Descriptive study of the prevalence of related factors of metabolic syndrome

劉世鴻(Shih-Hung Liu)

指導教授 ： 曾博修

中山醫學大學/醫學院/生化暨生物科技研究所/碩士(2012年)

摘要

本研究針對新陳代謝症候群採用橫斷式研究描述性分析進行探討，瞭解新陳代謝症候群的流行病學（盛行率）及相關危險因子，總共收集2,779份資料納入本次研究，男性族群與女性族群分成三種年齡層來探討：小於40 歲、40至64歲、與大於或等於65歲。統計方法採用t檢定與卡方檢定來檢定組間的差異。統計分析比較男性族群與女性族群三種年齡層於下列十一項參數之平均值、標準偏差、p值（年齡、身高、體重、身體質量指數、空腹血糖、總膽固醇、三酸甘油脂、高密度脂蛋白膽固醇、總膽固醇/高密度脂蛋白膽固醇、收縮壓、舒張壓）及比較男性族群與女性族群三種年齡層於下列七項參數各參考區間之個數、盛行率、p值（身體質量指數、總膽固醇、總膽固醇/高密度脂蛋白膽固醇、血壓「收縮壓、舒張壓」、空腹血糖、三酸甘油脂、高密度脂蛋白膽固醇）。
從分析結果可發現男性族群三種年齡層在平均身高、平均體重、收縮壓<130或舒張壓<85、空腹血糖<100有隨年齡增加而下降的趨勢，而在平均空腹血糖、平均收縮壓、收縮壓>130或舒張壓>85、空腹血糖>=100有隨年齡增加而升高的趨勢。
從分析結果可發現女性族群三種年齡層在平均身高、身體質量指數<18、身體質量指數18-23.9、總膽固醇<200、總膽固醇/高密度脂蛋白膽固醇<5、收縮壓<130或舒張壓<85、空腹血糖<100、三酸甘油脂<150、高密度脂蛋白膽固醇>=50有隨年齡增加而下降的趨勢，而在平均體重、平均身體質量指數、平均空腹血糖、平均總膽固醇、平均三酸甘油脂、平均總膽固醇/高密度脂蛋白膽固醇、平均收縮壓、平均舒張壓、身體質量指數24-27、身體質量指數>27、總膽固醇>=200、總膽固醇/高密度脂蛋白膽固醇>=5、收縮壓>130或舒張壓>85、空腹血糖>=100、三酸甘油脂>=150、高密度脂蛋白膽固醇<50有隨年齡增加而升高的趨勢。
從分析結果可發現男性族群三種年齡層在身體質量指數24-27、身體質量指數>27的盛行率分別為36.8%及22.6%，佔男性族群59.4%；在總膽固醇>=200的盛行率為52.8%；在收縮壓>130或舒張壓>85的盛行率為53.6%。
從分析結果可發現女性族群三種年齡層在總膽固醇>=200的盛行率為53.1%。
本次研究結論可發現在新陳代謝症候群相關因素盛行率之描述性研究上，男性族群與女性族群在各相關因素之盛行率仍有差異，在女性族群各相關因素之盛行率會隨年齡層增加而呈現邏輯性下降或升高的結論，而在男性族群各相關因素之盛行率較無呈現隨年齡層增加邏輯性下降或升高的結論，但是男性族群在身體質量指數24-27與身體質量指數>27（59.4%）、總膽固醇>=200（52.8%）、收縮壓>130或舒張壓>85（53.6%）的整體盛行率均超過50%以上，而女性族群只在總膽固醇>=200（53.1%）的整體盛行率超過50%以上，依據本次研究結論可推論男性族群符合新陳代謝症候群比例較女性族群高。

關鍵字

新陳代謝症候群 ； 橫斷式研究 ； 描述性分析 ； 流行病學 ； 盛行率 ； 危險因子

並列摘要

The descriptive analysis (the cross-sectional study) explored the epidemiology (prevalence) and related risk factors of the metabolic syndrome. In total, 2,779 data were enrolled in this study. Male group and female group divided into three age groups: less than 40 years, 40-64 years old, and greater than or equal to 65 years. Data were analyzed by the t test, chi-square test. Comparative analysis of the average, standard deviation, p values of the three age groups of male group and female group (age, height, weight, body mass index, fasting glucose, total cholesterol, triglyceride, high density lipoprotein cholesterol, total cholesterol / high density lipoprotein cholesterol, systolic blood pressure, diastolic blood pressure). Comparative analysis of the numbers, prevalence, p values of the three age groups of male group and female group (body mass index, total cholesterol, total cholesterol / high density lipoprotein cholesterol, systolic blood pressure, diastolic blood pressure, fasting glucose, triglycerides, high density lipoprotein cholesterol).
From the results of the analysis can be found in height, weight, systolic blood pressure <130 or diastolic blood pressure <85, fasting plasma glucose <100 with a downward trend in the the three age groups of male group, and in fasting blood glucose, the systolic blood pressure, systolic blood pressure> 130 or diastolic blood pressure> 85, fasting blood glucose> = 100 with a increase trend in the the three age groups of male group.
From the results of the analysis can be found in height, body mass index <18, body mass index 18-23.9, total cholesterol <200, total cholesterol / high density lipoprotein cholesterol <5, systolic blood pressure <130 or diastolicpressure <85, fasting plasma glucose <100, triglycerides <150, high density lipoprotein cholesterol> = 50 with a downward trend in the the three age groups of female group, and in weight, body mass index, fasting blood glucose, total cholesterol, triglyceride , total cholesterol / high density lipoprotein cholesterol, systolic blood pressure, diastolic blood pressure, body mass index 24-27, body mass index> 27, total cholesterol> = 200, total cholesterol / high density lipoprotein cholesterol > =5, systolic blood pressure> 130 or diastolic blood pressure> 85, fasting blood glucose> = 100, triglycerides> = 150, high-density lipoprotein cholesterol <50 with a increase trend in the the three age groups of female group.
From the results of the analysis can be found the prevalence of body mass index 24-27 , body mass index> 27 were 36.8% and 22.6%, accounted for 59.4% of the male group; the prevalence of total cholesterol> = 200 was 52.8%; the prevalence of systolic blood pressure> 130 or diastolic blood pressure> 85 was 53.6% in the the three age groups of male group.
From the results of the analysis can be found the prevalence of total cholesterol> = 200 was 53.1% in the the three age groups of female group.
The conclusion of the descriptive analysis can be found the prevalence and the related risk factors of the metabolic syndrome are still differences in the male and female group.Present the logical conclusion of decreased or increased in the prevalence of the related risk factors of the female group, but male group had no the effect.Body mass index 24-27 and body mass index> 27 (59.4%), total cholesterol> = 200 (52.8%), systolic blood pressure> 130 or diastolic blood pressure> 85 (53.6%) overall prevalence are more than 50% in the male group, but the female group only in the overall prevalence of total cholesterol> = 200 (53.1%) more than 50%.The male group in line with the proportion of metabolic syndrome is higher than the female group in accordance with the conclusions can be inferred.

並列關鍵字

Metabolic Syndrome ； Cross-section Survey ； Descriptive Analysis ； Epidemiology ； Prevalence ； Risk Factor

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