幾丁聚醣與海藻膠包覆辛夷精油的微膠囊成型製備及擴散緩釋性之 探討

The diffusion study of Magnolia liliiflora essential oil microencapsulated in the Chitosan / Alginate Composites.

徐秀蘭(Hsiu-Lan Hsu)

指導教授 ： 芮祥鵬

國立臺北科技大學/工程學院/有機高分子研究所/碩士(2012年)

https://doi.org/10.6841/NTUT.2012.00011

摘要

本研究探討微膠囊包覆辛夷精油之成型製備與改變不同參數條件得到辛夷精油擴散係數D值，以幾丁聚醣(Chitosan)與海藻膠(Alginate)做為微膠囊包覆殼材，將天然辛夷精油為可包覆的芯材，實驗以正負電解質凝膠交聯複合反應(Gel cross-link -complex reaction)，進行離子交聯（Ionic cross-linking）反應製備精油複合微膠囊。微膠囊中的辛夷精油的擴散釋放特性，其符合氣體擴散第二定律(Fick’s second Law)之模式;實驗中製備精油標準校正曲線(Standard calibration curve)，得到標準精油濃度與釋放強度公式。改變二氯化鈣、海藻酸鈉、幾丁聚醣(Chitosan)之添加量比例等操作參數，影響複合微膠囊之精油擴散釋放模式及擴散係數D值之探討。
各包覆物之間的組成比例會影響到微膠囊的精油擴散係數D值，尤以幾丁聚醣(chitosan)濃度影響最大，當濃度越低的情況下能使微膠囊中精油擴散係數D值為0.00262mm2.sec-1，當幾丁聚醣濃度為0.6%(w/w) ，微膠囊中精油擴散係數D值為0.000763mm2.sec-1。在不同溫度下，受溫度影響有不同的擴散係數D值，25℃時D值為0.000646 mm2.sec-1。50℃時D值為0.002230 mm2.sec-1。藉由調整微膠囊的簡單出孔孔徑可控制粒徑大小，同時製備出不同粒徑大小的微膠囊，來得到該微膠囊精油的擴散係數D值為0.001643 mm2.sec-1。以此微膠囊包覆技術來製備精油微膠囊顆粒（gel beads），確實達到有效包覆精油的擴散釋放及得到各參數條件的擴散係數D值。

關鍵字

微膠囊 ； 辛夷精油 ； 幾丁聚醣 ； 海藻膠

並列摘要

This thesis investigates the molding preparation of microcapsules magnolia
essential oils and change the different parameters of the essential oil diffusion coefficient D values, the microcapsules with chitosan and sodium alginate as the shell material, natural magnolia The essential oil of the core material can be coated, cross-linked complex reaction experiment, positive and negative electrolyte gel, ionic crosslinking reaction Preparation of essential oils composite microcapsules.
Magnolia the diffusion of essential oil concentration in the microcapsule -characteristics, compliance with the gas diffusion to the second law mode; experiment in the preparation of essential oil standard calibration curve standard essential oil concentration and release strength formula. Change of two calcium chloride, sodium alginate, chitosan, add the amount of the proportion of operating parameters, diffusion release model and the diffusion coefficient D value of impact composite microcapsules of essential oils.
Between the various coverings, the composition ratio will affect the microcapsules of essential oils diffusion coefficient D values, especially the concentration of chitosan the greatest impact, make the microcapsules in the case of the lower concentration in the oil diffusion coefficient D The value 0.00262mm2/sec, when the chitosan concentration of 0.60% (w / w), microcapsules, essential oil diffusion coefficient D the value 0.000763mm2/sec. Affected by temperature, different values for the diffusion coefficient D at different temperatures, the D value of 0.002230 mm2/sec at 50℃，at 25℃，when the D value of 0.000646 mm2/sec. By simple adjustment microcapsules out hole diameter can be controlled particle size, and preparation of different particle size of microcapsules, the microcapsules of essential oils diffusion coefficient D value is .0986 mm2/sec . In order the microcapsules techniques to prepare essential oils microcapsule particles (gel beads,) really effectively coated essential oils diffusion release and diffusion coefficient D values of each parameter conditions.

並列關鍵字

Microencapsule ； Magnolia liliiflora essential oil ； Chitosan ； Alginate

參考文獻

參考文獻

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