利用高效率直流轉換及整流器之高壓電刺激器晶片

近年生醫產業及研發蓬勃發展，其中引人注目的電刺激治療器可以突破傳統醫學上只有吃藥打針治病的治療方法，它是結合了生物醫學及電子工程科學而衍生出新的醫療裝置。本論文研究之電刺激治療器，為了實現植入式電療方法，本論文晶片係利用諧振與線圈的電磁耦合原理，以無線方式傳遞能量，將耦合到的能量轉換並提供晶片整體使用，再進一步將能量升壓輸出，旨在實現一個可應用於植入式生醫裝置之無線電源管理電路，以及產生一個可應用於電刺激治療的PRF脈衝式射頻電刺激控制訊號。本晶片可分為類比以及數位兩部分：類比電路分別為主動開關式整流電路以及切換式升壓直流轉換器電路，其中切換式升壓直流轉換器包含誤差放大器、比較器、三角波產生電路、精簡型三角波產生電路、脈波寬度調變電路、驅動電路。而數位部分則是PRF電刺激控制訊號產生電路。此晶片利用TSMC 2P4M 0.35um CMOS製程實現，其中主動開關式整流電路輸出3.3V，效率可達90.8%。升壓直流轉換器可輸出10V，效率可達92.5%。數位訊號可輸出一個刺激脈波頻率為500KHz，其刺激脈波週期為2Hz，刺激時間為20ms，刺激強度為3.3V的PRF刺激控制訊號。總晶片面積為2.38mm*2.3mm，整體效率為65%。

關鍵字

電場耦合；電刺激；整流；升壓；脈衝式射頻

並列摘要

In the view point of the increasing aging population, biomedical and biological researches are vigorously growing in the recent year in Taiwan. The eye-catching electronic stimulator can break through the traditional medical treatments, which always uses injection and medicine. The electronic stimulator combined the biological science with the electronic engineering science to develop brand-new medical applications. In order to implement for implanted electrotherapy device, this thesis utilizing the coupling coils to realize the wireless energy transmission. The proposed chip can be self-sufficiency by rectifying the coupling energy and boosting the DC voltage to a high output level. The purpose of this chip is to realize a wireless power management circuits and a PRF (Pulsed Radio Frequency) control signal generator used in stimulator for implanted biomedical devices. This chip can divide into analog and digital circuit blocks. Analog circuits include the active switching rectifier and switching DC-DC boost converter. The boost converter is consisted of an error amplifier, a comparator, a ramp generator, a PWM generator and driver. The PRF generator is also realized in the digital circuit. This chip was fabricated TSMC 2P4M 0.35 um Mixed-Signal CMOS process. The rectifier can export 3.3V and it power efficiency achieves 90.8%. The DC-DC boost converter outputs 10V supply with high efficiency 92.5%. The PRF circuit can deliver a pulsed waveform with a 500 KHz carrier frequency, 2Hz period and 20ms stimulation duration at an intensity of 3.3V. The whole chip size is 2.38mm*2.3mm and the whole power conversion efficiency is 65%.

並列關鍵字

Wireless Coupling ； Stimulator ； Rectify ； Boost ； PRF

參考文獻

[21] 林木鍊，植入式脈衝射頻電刺激與微型導航系統於下背痛之臨床應用，博士論文，國立台灣大學醫學工程研究所，台北，2011。

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國際替代計量

利用高效率直流轉換及整流器之高壓電刺激器晶片

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