含奈米銀粒子之靜電紡絲水膠奈米纖維其及在抗菌消臭之應用

The electrospun nanofibers from hydrogel copolymers with Ag particles and their antimicrobial and deodorizing application

謝秀伶(Hsieh,Hsiu-ling)

指導教授 ： 郭霽慶

國立臺北科技大學/工程學院/有機高分子研究所/碩士(2014年)

https://doi.org/10.6841/NTUT.2014.00784

摘要

靜電紡絲技術是近年新穎的奈米科技，材料來源廣泛且製程簡單，擁有能夠快速直接地將材料製備成奈米纖維的特質，並無傳統纖維製程之限制。近年來已經成為高分子工程上一個非常重要的研究主題。高分子的微細結構決定了成品的應用範圍，而除了材料本身的性質外，在加工過程中的各種因子也會影響到高分子微細結構的改變。研究中使用Poly（HEMA-co-NMA）共聚高分子為主體，摻合硝酸銀使之具有抗菌及消臭性。經由靜電紡絲製成奈米化纖維膜，並將樣品進行SEM、UV光還原、交聯、泡水、抗菌性與消臭性測試。
本研究成功利用Poly（HEMA-co-NMA）共聚高分子為主體（HEMA為高吸水性基團，而NMA為化學交聯基團），摻合硝酸銀後照UV光還原，得到不同比例的含銀奈米粒子的奈米纖維不織布。藉由調控不同的電紡操作參數（不同溶液濃度、添加溶劑Methanol量、電紡流速）、加熱溫度以及奈米纖維厚度控制，製得多樣化形態與纖維細度範圍100~1000 nm的奈米纖維。
以JIS L1902:2008菌液吸收法，進行抗菌測試(金黃色葡萄球菌&大腸桿菌)和FTTS-FA-018-2008進行消臭測試。本研究結果可知，隨著奈米銀粒子添加濃度增加，金黃色葡萄球菌抑菌活性值隨之上升，添加3%的奈米銀粒子，可以達到最高抑菌值5.2（S）與殺菌值3.1（L）；大腸桿菌抑菌活性值隨之上升，添加3%的奈米銀粒子，可以達到最高抑菌值6.9（S）與殺菌值3.4（L），抗菌效果顯著。添加3 %的奈米銀粒子，消臭率24小時後可達30 %的消臭率，具有環保及低成本之特性。未來，此奈米級纖維膜期望能應用在醫療衛生用品及生化生醫等材料。

關鍵字

靜電紡絲 ； 硝酸銀 ； 奈米纖維 ； 抗菌 ； 消臭

並列摘要

Electrospinning technique is novel nanotechnology in recent years, a wide range of source materials and the manufacturing process is simple, has a trait can be prepared quickly and directly into nano-fiber material, there is no limit to the tradition fiber manufacturing process. In recent years has become a very important topic of polymer engineering research. The fine structure of the polymer determines the scope of application of the finished product, and in addition to the nature of the material itself order to various factors in the process of change will also affect the fine structure of the polymer. Studies using Poly (HEMA-co-NMA) copolymers as the main blending silver nitrate to make and has antibacterial deodorizing. Formed by the electrostatic spinning of nano fiber web film. Then testing include SEM, UV light reduction, crosslinked, immersed, antibacterial test and deodorizing test.
The study successfully using Poly (HEMA-co-NMA) copolymer as the main polymer (HEMA of superabsorbent group, and NMA of chemical crosslinking group), according to the UV light by blending a silver nitrate is reduced to give containing different proportions nano fibers are not woven silver nanoparticles. By regulating different electrospinning operating parameters (different solution concentrations, the amount of added solvent Methanol, electro-spinning velocity), heating temperature, and controlling nano fiber thickness, to obtain diverse morphology and fiber fineness range of 100 ~ 1000 nm nano fibers.
With JIS L1902: 2008 bacteria absorption, antibacterial test (Staphylococcus aureus & Escherichia coli) and FTTS-FA-018-2008 deodorizes test. The results of this study, when increasing concentration of the silver nanoparticles, and Staphylococcus aureus antibacterial activity values rise, then adding 3% of silver nanoparticles, getting a maximum inhibition value of 5.2 (S) and maximum sterilization value of 3.1 (L). When adding 3% of silver nanoparticles , the Escherichia coli antibacterial activity value was rise, can reach a maximum inhibition value 6.9 (S) , sterilization value 3.4 (L), and after 24 hours of deodorizing rate was up to 30% , has the characteristics of environmental protection and low cost. Future, the nano-fibers in the film expect to medical supplies and biochemical raw materials such as clothing.

並列關鍵字

Electrospinning ； silver nitrate ； nanofiber ； antibacterial ； deodorizing

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